| 703 | 0 | 95 |
| 下载次数 | 被引频次 | 阅读次数 |
目的 了解贵州省19～59岁人群流感疫苗(Influenza vaccine,InfV)犹豫现状及其影响因素。方法 采用多阶段整群抽样方法在贵州省19个区县选取19～59岁人群开展InfV犹豫量表问卷调查，分析InfV犹豫量表得分(满分为30分)及其影响因素。结果 调查对象InfV犹豫量表得分中位数(四分位数间距)为15(12～18)分。多因素分析显示，非医务工作者、农村居住者、有饮酒史者、既往疫苗接种有不适症状者、看过疫苗事件相关媒体报道者犹豫量表得分更高[β(95%CI):2.27(1.43～3.12)、0.69(0.09～1.28)、0.89(0.28～1.94)、1.71(1.08～2.34)、0.74(0.11～1.37)];亲人或朋友推荐过InfV者犹豫量表得分更低[β(95%CI):-1.14(-1.77～-0.51)]。结论 贵州省19～59岁人群InfV犹豫程度偏高，需加强该人群流感和InfV接种相关知识健康教育，以提高疫苗素养，降低InfV犹豫。
Abstract：Objective To explore influenza vaccine( Inf V) hesitancy and factors influencing hesitancy among people 19-59 years of age in Guizhou province. Methods We used a multi-stage cluster sampling method to recruit 19-59-year-olds from 19 counties/districts of Guizhou for a questionnaire-based survey that used a modified InfV hesitancy scale. We analyzed hesitancy scores( full score was 30 points) and identified factors influencing hesitancy. Results The median( interquartile range) score of InfV hesitancy was 15( 12 to18) points. Multivariate analysis showed that hesitancy was higher among respondents who were non-medical staff,who were rural residents,who had a drinking history,who had experienced vaccine reactions,and who had ever read media reports related to vaccine events [β( 95% CI) : 2.27( 1.43 to 3.12),0.69( 0.09 to 1.28),0.89( 0.28 to 1.94),1.71( 1.08 to 2.34),0.74( 0.11 to 1.37) ]. Hesitancy was lower among respondents who had been recommended for InfV vaccination by their relatives/friends [β( 95% CI) :-1.14(-1.77 to-0.51) ]. Conclusions The level of InfV hesitancy was high among people 19-59 years of age in Guizhou. It is necessary to strengthen health education on influenza and InfV-related knowledge for this group to increase vaccine literacy and reduce vaccine hesitancy.
[1]中华人民共和国国家卫生健康委员会，国家中医药管理局．流行性感冒诊疗方案(2025年版)[J]．中国感染控制杂志，2025,24(2):290-294. DOI:10. 12138/j. issn. 1671-9638.20257379.
[2]World Health Organization. Influenza(seasonal)[EB/OL].(2025-02-28)[2025-07-30]. https://www. who. int/en/newsroom/fact-sheets/detail/influenza-(seasonal).
[3]宋祎凡，张肇南，胡入月，等．中国2010-2022年非国家免疫规划疫苗接种变化趋势分析[J]．中国疫苗和免疫，2025,31(1):1-7. DOI:10. 19914/j.CJVI.2025001.
[4]Hou Z,Guo J,Lai X,et al. Influenza vaccination hesitancy and its determinants among elderly in China:a national crosssectional study[J]. Vaccine,2022,40(33):4806-4815. DOI:10. 1016/j.vaccine.2022. 06. 063.
[5]许濒月，龙江，柏宁培，等．2023年重庆市0-6岁儿童监护人疫苗犹豫现状和影响因素调查[J]．中国疫苗和免疫，2024,30(2):155-159. DOI:10. 19914/j.CJVI.2024023.
[6]倪平，陈京立，刘娜．护理研究中量性研究的样本量估计[J]．中华护理杂志，2010, 45(4):378-380. DOI:10. 3761/j.issn.0254-1769. 2010. 04. 037.
[7]倪延延，张晋昕．假设检验时样本含量估计中容许误差δ的合理选取[J]．循证医学，2011,11(6):370-372.
[8]彭淋，陈文静，谢伟光，等．2019年东莞市儿童家长疫苗犹豫及其影响因素调查[J]．中国疫苗和免疫，2024,30(1):49-53. DOI:10. 19914/j.CJVI.2024010.
[9]Larson HJ,Jarrett C,Schulz WS,et al. Measuring vaccine hesitancy:the development of a survey tool[J]. Vaccine,2015,33(34):4165-4175. DOI:10. 1016/j.vaccine.2015. 04. 037.
[10]黄依漫．中国新型冠状病毒疫苗犹豫现状及其影响因素:一项多中心研究[D]．北京:北京协和医学院，2023. DOI:10. 27648/d.cnki.gzxhu.2023. 000634.
[11]Zou H,Huang Y,Chen T,et al. Influenza vaccine hesitancy and influencing factors among university students in China:a multicenter cross-sectional survey[J]. Ann Med,2023,55(1):2195206. DOI:10. 1080/07853890. 2023. 2195206.
[12]陈楚颖，魏来，冯毅，等．贵州省卫生资源配置结构及公平性研究[J]．现代预防医学，2022,49(1):88-91+102.
[13]Fang P,Zheng H,Liu L,et al. Factors influencing knowledge and acceptance of nonavalent human papillomavirus vaccine among university population in southern China:a cross-sectional study[J]. Cancer Control, 2024, 31:10732748241293989.DOI:10. 1177/10732748241293989.
[14]Yang J,Jit M,Leung KS,et al. The economic burden of influenza-associated outpatient visits and hospitalizations in China:a retrospective survey[J]. Infect Dis Poverty,2015,4:44. DOI:10. 1186/s40249-015-0077-6.
[15]Li Z,Tian Y,Gong Z,et al. Health literacy and regional heterogeneities in China:a population-based study[J]. Front Public Health, 2021, 9:603325. DOI:10. 3389/fpubh.2021. 603325.
[16]姚志臻，张斌，司湘云．基于网络问答社区的疫苗情绪语义网络分析[J]．信息资源管理学报，2021,11(1):70-79.DOI:10. 13365/j.jirm.2021. 01. 070.
[17]Daley MF,Narwaney KJ,Shoup JA,et al. Addressing parents'vaccine concerns:a randomized trial of a social media intervention[J]. Am J Prev Med,2018,55(1):44-54. DOI:10. 1016/j.amepre.2018. 04. 010.
[18]Alvarez FP,Chevalier P,Borms M,et al. Cost-effectiveness of influenza vaccination with a high dose quadrivalent vaccine of the elderly population in Belgium,Finland,and Portugal[J]. J Med Econ, 2023, 26(1):710-719. DOI:10. 1080/13696998. 2023. 2194193.
[19]Neufeind J,Betsch C,Zylka-Menhorn V,et al. Determinants of physician attitudes towards the new selective measles vaccine mandate in Germany[J]. BMC Public Health,2021,21(1):566. DOI:10. 1186/s12889-021-10563-9.
[20]Wang C,Han B,Zhao T,et al. Vaccination willingness,vaccine hesitancy,and estimated coverage at the first round of COVID-19vaccination in China:a national cross-sectional study[J].Vaccine,2021,39(21):2833-2842. DOI:10. 1016/j.vaccine.2021. 04. 020.
[21]熊丽，邓莉芳，许乐为，等．江西省脱贫地区初中生健康素养水平与饮酒行为的关联分析[J]．中国健康教育，2024,40(12):1097-1101. DOI:10. 16168/j. cnki. issn. 1002-9982. 2024. 12. 008.
[22]Desai S,Kainth T,Yadav G,et al. Role of psychosomatic symptoms in COVID-19 vaccine hesitancy[J]. Vaccines(Basel),2023,11(5):922. DOI:10. 3390/vaccines11050922.
[23]Du F,Chantler T,Francis MR,et al. The determinants of vaccine hesitancy in China:a cross-sectional study following the Changchun Changsheng vaccine incident[J]. Vaccine,2020,38(47):7464-7471. DOI:10. 1016/j.vaccine.2020. 09. 075.
[24]赵天朔，刘翰谕，郑徽，等．中国3个地区儿童家长对国家免疫规划类疫苗犹豫现状研究[J]．中华流行病学杂志，2021,42(9):1615-1620. DOI:10. 3760/cma. j. cn112338-20210108-00017.
[25]Santavicca T,Ngov C,Frounfelker R,et al. COVID-19 vaccine hesitancy among young adults in Canada[J]. Can J Public Health,2023,114(1):10-21. DOI:10. 17269/s41997-022-00693-x.
基本信息:
DOI：10.19914/j.CJVI.2025105
中图分类号:R186
引用信息:
[1]王云昭,伍丙兰,肖燕,等.2025年贵州省19～59岁人群流感疫苗犹豫现状及其影响因素调查[J].中国疫苗和免疫,2025,31(06):666-670.DOI:10.19914/j.CJVI.2025105.
基金信息:
北大-默沙东传染病防控技术联合实验室医学创新基金项目(10001202411)
2025-12-26
2025-12-26